|
| |
Use a molecule from the Fragment Library to build another
molecule
Task: Build
-- Part 1
Time: 10 minutes
- Select File|Open and
open the Fragment
Library folder.
- Open the Cyclic folder.

- Choose cyclopentane.csf and click Open. A document window
opens with a model of cyclopentane.

- Before making any changes, we want to save our molecule, and we
want to be sure to save it with its new name in the appropriate folder.
- Select
File|Save as.
- Locate the folder where you want to store the
molecule.
- Name the file "nitrocyclo".
Click Save.
- Change the two C-C single bonds to C=C double bonds.
- Using the
select tool, click on one bond.
- Hold down the shift key and click on the second bond (see picture above).
- Select
in Bond Type box.
- Change the hybridization of the carbon atoms with C=C double bonds.
- Using the select tool, click on one carbon atom.
- Hold down the shift key and click on the other carbon atoms in the double
bonds.
- Select
in Hybridization box.
- Click in the Workspace (no atoms or bonds) to select the whole molecule Select Beautify|Comprehensive.
- Save the changes you have made so far. Select File|Save.
- We want to add a nitro group. We could just build it by replacing
one of the hydrogen atoms with a nitrogen and then adding the oxygen atoms.
OR, we could use the nitro group from the Fragment Library.
In the next lesson we will add a nitro group
from the Fragment Library to
the cyclopentadiene fragment we just made.
|